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Apex Nursing

Anion Gap Calculator

Na − (Cl + HCO₃), with optional albumin correction for the true expected gap.

mEq/L
mEq/L
mEq/L
g/dL

Enter sodium, chloride, and bicarbonate to calculate.

High-gap causes — MUDPILES

Methanol · Uremia · DKA · Propylene glycol · Iron / INH · Lactic acidosis · Ethylene glycol · Salicylates

Lactic acidosis and DKA dominate at the bedside — a high gap should send you to the lactate, glucose, and ketones first.

Educational use only. Acid-base interpretation supports — never replaces — the ABG, the clinical picture, and provider evaluation. This material supports nursing education and exam review. It is not medical advice and is not a substitute for clinical judgment, institutional policy, or medical direction. Always follow facility protocols and current provider orders.