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Apex Nursing

Chart — Hematology

Leukemia Types Comparison Chart

Two axes sort all four leukemias: speed (acute vs chronic) and cell line (myeloid vs lymphoid). Memorize the hallmark clue for each and the type questions answer themselves.

Educational use only. Treatment approaches are individualized and provider-directed. This chart is an educational comparison aid. This material supports nursing education and exam review. It is not medical advice and is not a substitute for clinical judgment, institutional policy, or medical direction. Always follow facility protocols and current provider orders.

The Four Types

TypeCourseCell lineTypical ageHallmarkTreatment
AML (acute myeloid)AcuteMyeloidAdults (most common acute leukemia in adults); risk rises with ageAuer rods; rapid marrow failureIntensive induction chemo ± HSCT
ALL (acute lymphoblastic)AcuteLymphoidChildren (most common childhood cancer); also adultsCNS involvement risk; bone painMultiphase chemo + CNS prophylaxis ± HSCT
CML (chronic myeloid)ChronicMyeloidMiddle-aged/older adultsPhiladelphia chromosome (BCR-ABL); blast crisis riskTyrosine kinase inhibitors (imatinib)
CLL (chronic lymphocytic)ChronicLymphoidOlder adults (most common adult leukemia)Often incidental lymphocytosis; smudge cellsWatchful waiting → targeted therapy/chemo

Exam Traps

  • Auer rods = AML; Philadelphia chromosome (BCR-ABL) = CML (treated with tyrosine kinase inhibitors).
  • ALL = most common childhood cancer; CLL = most common adult leukemia (older adults).
  • Acute = blasts dominate, aggressive, marrow fails fast; chronic = more mature cells, slower.
  • Whatever the type, the shared danger is the triad: anemia, neutropenia, thrombocytopenia.
  • Neutropenic fever in any leukemia patient = emergency (cultures + antibiotics within 1 hour).

Related Resources

Standards & sources

Fact-checked Jun 21, 2026

This page is written to align with AABB (transfusion standards) · American Society of Hematology (ASH). It is an educational summary, not a citation of any single document — always verify specific doses, values, and protocols against current guidelines and your facility policy. How we source content →